Strength of Schedule Rankings: 2006 National Football League (NFL)
Week 2 | Week 3 | Week 4 | Week 5 | Week 6 | Week 7 | Week 8 | Week 9 | Week 10 | Week 11 | Week 12 | Week 13 | Week 14 | Week 15 | Week 16 | Week 17 | Final
Strength of schedule (SOS) scores include only games that have already been played. Games still remaining on the schedule do not impact the present week's strength of schedule scores. For this reason, SOS scores are not made available before the completion of the second week.
| Rank | Program | Score | Division | # Games | Non-Division Games |
| 1. | New York Giants |
700.81 | #1 NFC East | 3 | #1 Indianapolis Colts @ #5 Seattle Seahawks |
| 2. | Jacksonville Jaguars |
648.11 | #5 AFC South | 4 | #9 Dallas Cowboys #14 Pittsburgh Steelers @ #16 Washington Redskins |
| 3. | Tampa Bay Buccaneers |
617.22 | #4 NFC South | 3 | #7 Baltimore Ravens |
| 4. | Denver Broncos |
579.79 | #3 AFC West | 3 | @ #19 St. Louis Rams @ #6 New England Patriots |
| 5. | New England Patriots |
579.04 | #6 AFC East | 4 | #4 Denver Broncos @ #3 Cincinnati Bengals |
| 6. | Kansas City Chiefs |
577.13 | #3 AFC West | 3 | #3 Cincinnati Bengals #28 San Francisco 49ers |
| 7. | Minnesota Vikings |
570.94 | #8 NFC North | 4 | @ #16 Washington Redskins #12 Carolina Panthers @ #21 Buffalo Bills |
| 8. | Pittsburgh Steelers |
569.40 | #2 AFC North | 3 | #26 Miami Dolphins @ #8 Jacksonville Jaguars |
| Rank | Program | Score | Division | # Games | Non-Division Games |
| 9. | Detroit Lions |
559.44 | #8 NFC North | 4 | #5 Seattle Seahawks @ #19 St. Louis Rams |
| 10. | Houston Texans |
545.18 | #5 AFC South | 4 | #17 Philadelphia Eagles #16 Washington Redskins #26 Miami Dolphins |
| 11. | Washington Redskins |
526.79 | #1 NFC East | 4 | #15 Minnesota Vikings @ #27 Houston Texans #8 Jacksonville Jaguars |
| 12. | Arizona Cardinals |
523.15 | #7 NFC West | 4 | @ #11 Atlanta Falcons |
| 13. | Oakland Raiders |
520.89 | #3 AFC West | 3 | @ #7 Baltimore Ravens #24 Cleveland Browns |
| 14. | Cincinnati Bengals |
518.19 | #2 AFC North | 4 | @ #18 Kansas City Chiefs #6 New England Patriots |
| 15. | Cleveland Browns |
518.16 | #2 AFC North | 4 | #20 New Orleans Saints @ #30 Oakland Raiders |
| 16. | New York Jets |
506.80 | #6 AFC East | 4 | @ #32 Tennessee Titans #1 Indianapolis Colts |
| Rank | Program | Score | Division | # Games | Non-Division Games |
| 17. | Buffalo Bills |
488.51 | #6 AFC East | 4 | #15 Minnesota Vikings |
| 18. | Indianapolis Colts |
485.67 | #5 AFC South | 4 | @ #10 New York Giants @ #22 New York Jets |
| 19. | Carolina Panthers |
484.26 | #4 NFC South | 4 | @ #15 Minnesota Vikings |
| 20. | Tennessee Titans |
479.38 | #5 AFC South | 4 | #22 New York Jets @ #13 San Diego Chargers @ #26 Miami Dolphins #9 Dallas Cowboys |
| 21. | Green Bay Packers |
475.80 | #8 NFC North | 4 | #20 New Orleans Saints @ #17 Philadelphia Eagles |
| 22. | Seattle Seahawks |
461.07 | #7 NFC West | 4 | @ #31 Detroit Lions #10 New York Giants @ #2 Chicago Bears |
| 23. | San Francisco 49ers |
453.10 | #7 NFC West | 4 | #17 Philadelphia Eagles @ #18 Kansas City Chiefs |
| 24. | Dallas Cowboys |
442.35 | #1 NFC East | 3 | @ #8 Jacksonville Jaguars @ #32 Tennessee Titans |
| Rank | Program | Score | Division | # Games | Non-Division Games |
| 25. | New Orleans Saints |
427.19 | #4 NFC South | 4 | @ #24 Cleveland Browns @ #29 Green Bay Packers |
| 26. | Atlanta Falcons |
422.79 | #4 NFC South | 4 | #25 Arizona Cardinals |
| 27. | Chicago Bears |
411.00 | #8 NFC North | 4 | #5 Seattle Seahawks |
| 28. | St. Louis Rams |
353.50 | #7 NFC West | 4 | #4 Denver Broncos #31 Detroit Lions |
| 29. | Baltimore Ravens |
337.02 | #2 AFC North | 4 | @ #23 Tampa Bay Buccaneers #30 Oakland Raiders #13 San Diego Chargers |
| 30. | Miami Dolphins |
335.00 | #6 AFC East | 4 | @ #14 Pittsburgh Steelers #32 Tennessee Titans @ #27 Houston Texans |
| 31. | San Diego Chargers |
332.41 | #3 AFC West | 3 | #32 Tennessee Titans @ #7 Baltimore Ravens |
| 32. | Philadelphia Eagles |
321.91 | #1 NFC East | 4 | @ #27 Houston Texans @ #28 San Francisco 49ers #29 Green Bay Packers |
@ indicates an away game
% indicates a neutral site game





