Strength of Schedule Rankings: 2006 National Football League (NFL)
Week 2 | Week 3 | Week 4 | Week 5 | Week 6 | Week 7 | Week 8 | Week 9 | Week 10 | Week 11 | Week 12 | Week 13 | Week 14 | Week 15 | Week 16 | Week 17 | Final
Strength of schedule (SOS) scores include only games that have already been played. Games still remaining on the schedule do not impact the present week's strength of schedule scores. For this reason, SOS scores are not made available before the completion of the second week.
| Rank | Program | Score | Division | # Games | Non-Division Games |
| 1. | Kansas City Chiefs |
690.38 | #3 AFC West | 2 | #3 Cincinnati Bengals |
| 2. | Detroit Lions |
668.99 | #8 NFC North | 2 | #4 Seattle Seahawks |
| 3. | Carolina Panthers |
633.50 | #4 NFC South | 2 | @ #7 Minnesota Vikings |
| 4. | Washington Redskins |
629.57 | #2 NFC East | 2 | #7 Minnesota Vikings |
| 5. | Dallas Cowboys |
618.05 | #2 NFC East | 2 | @ #1 Jacksonville Jaguars |
| 6. | Jacksonville Jaguars |
605.96 | #5 AFC South | 2 | #13 Dallas Cowboys #8 Pittsburgh Steelers |
| 7. | Pittsburgh Steelers |
598.07 | #1 AFC North | 2 | #21 Miami Dolphins @ #1 Jacksonville Jaguars |
| 8. | Houston Texans |
589.45 | #5 AFC South | 2 | #19 Philadelphia Eagles |
| Rank | Program | Score | Division | # Games | Non-Division Games |
| 9. | Tampa Bay Buccaneers |
580.13 | #4 NFC South | 2 | #15 Baltimore Ravens |
| 10. | Oakland Raiders |
577.33 | #3 AFC West | 2 | @ #15 Baltimore Ravens |
| 11. | New York Giants |
573.07 | #2 NFC East | 2 | #2 Indianapolis Colts |
| 12. | Cleveland Browns |
549.19 | #1 AFC North | 2 | #24 New Orleans Saints |
| 13. | Buffalo Bills |
536.68 | #7 AFC East | 2 | none |
| 14. | Arizona Cardinals |
534.98 | #6 NFC West | 2 | none |
| 15. | Miami Dolphins |
524.22 | #7 AFC East | 2 | @ #8 Pittsburgh Steelers |
| 16. | Minnesota Vikings |
507.98 | #8 NFC North | 2 | @ #17 Washington Redskins #14 Carolina Panthers |
| Rank | Program | Score | Division | # Games | Non-Division Games |
| 17. | Atlanta Falcons |
501.24 | #4 NFC South | 2 | none |
| 18. | Tennessee Titans |
489.76 | #5 AFC South | 2 | #25 New York Jets @ #10 San Diego Chargers |
| 19. | St. Louis Rams |
479.23 | #6 NFC West | 2 | #6 Denver Broncos |
| 20. | Green Bay Packers |
466.27 | #8 NFC North | 2 | #24 New Orleans Saints |
| 21. | Indianapolis Colts |
451.83 | #5 AFC South | 2 | @ #5 New York Giants |
| 22. | Denver Broncos |
445.49 | #3 AFC West | 2 | @ #23 St. Louis Rams |
| 23. | Philadelphia Eagles |
430.34 | #2 NFC East | 2 | @ #30 Houston Texans |
| 24. | Cincinnati Bengals |
413.77 | #1 AFC North | 2 | @ #16 Kansas City Chiefs |
| Rank | Program | Score | Division | # Games | Non-Division Games |
| 25. | New York Jets |
406.78 | #7 AFC East | 2 | @ #32 Tennessee Titans |
| 26. | San Francisco 49ers |
399.17 | #6 NFC West | 2 | none |
| 27. | New England Patriots |
367.15 | #7 AFC East | 2 | none |
| 28. | Baltimore Ravens |
365.36 | #1 AFC North | 2 | @ #18 Tampa Bay Buccaneers #28 Oakland Raiders |
| 29. | Seattle Seahawks |
350.25 | #6 NFC West | 2 | @ #29 Detroit Lions |
| 30. | New Orleans Saints |
264.70 | #4 NFC South | 2 | @ #27 Cleveland Browns @ #31 Green Bay Packers |
| 31. | San Diego Chargers |
255.10 | #3 AFC West | 2 | #32 Tennessee Titans |
| 32. | Chicago Bears |
252.80 | #8 NFC North | 2 | none |
@ indicates an away game
% indicates a neutral site game





